Innate immunity is the first defense system against invading pathogens. Toll-like receptors (TLRs) are well-defined pattern recognition receptors responsible for pathogen recognition and induction of ...
Institut de Química Computacional i Catàlisi (IQCC) and Departament de Química, Universitat de Girona, Campus Montilivi, Girona E-17071, Catalonia, Spain ...
Study of 2.4 million participants reveals potential advantages for cardiometabolic and psychiatric conditions alongside increased risks of gastrointestinal and musculoskeletal issues Study ...
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School of Environmental Science and Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, P.R. China CAS Key Laboratory of Mineralogy and Metallogeny/Guangdong Provincial Key ...
The ∼45 olfactory neuron classes in Drosophila express different odorant receptors, which determine the range of odorants that the neurons sense. Axons from each class of olfactory neurons project to ...
The ubiquitous P-loop fold nucleoside triphosphatases (NTPases) are typically activated by an arginine or lysine ‘finger’. Some of the apparently ancestral NTPases are, instead, activated by potassium ...
For two of its most studied substrates, the Notch receptor and the amyloid precursor protein (APP), γ-secretase performs ... 2014), the active site appeared to be in an inactive conformation as the ...