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Hepatitis B (sometimes referred to as hep B) is a liver infection caused by the hepatitis B virus (HBV). It typically causes symptoms like stomach pain, dark urine, fatigue, fever, jaundice (yellowing ...
School of Environment and Civil Engineering, Dongguan University of Technology, Dongguan 523808, P. R. China Guangdong Key Laboratory of Nanomedicine, CAS-HK Joint Lab of Biomaterials, CAS Key ...
(31) treated human PBMCs in vitro with the prodrug OME 12.5–50 µg/mL for 4–24 h to assess cytokine production, phagolysosomal acidification, and transcriptomic analysis ... from macrophages, ...
Autophagy involves the formation of autophagosomes, double-membraned vesicles that engulf damaged organelles, misfolded proteins, and pathogens for degradation in the lysosomes (Levine and Kroemer ...
When news broke in 2014 that hepatitis C, a viral disease affecting the liver, could be cured thanks to a new class of direct-acting antiviral drugs, many began to wonder how soon it would be before ...
While PSEN1 prefers to bask on the cell surface and sometimes ventures into the early endosomes, PSEN2 contains a sorting sequence that strictly restricts it to late endosomes and lysosomes. As such, ...
Ocean acidification is an urgent environmental challenge caused by rising atmospheric carbon dioxide (CO2) levels, mainly due to human activities. It involves a continuous decrease in the pH of ocean ...
Studies have shown that ocean water is more acidic now than in pre-industrial times and is predicted to approach levels not seen in millions of years. This is known as ocean acidification. Ocean ...
The rise in carbon dioxide (CO2) levels in our world’s atmosphere is fueling an environmental threat to marine life. Ocean acidification is growing in magnitude as it moves into deeper waters. Jens ...