School of Environment and Civil Engineering, Dongguan University of Technology, Dongguan 523808, P. R. China Guangdong Key Laboratory of Nanomedicine, CAS-HK Joint Lab of Biomaterials, CAS Key ...

(31) treated human PBMCs in vitro with the prodrug OME 12.5–50 µg/mL for 4–24 h to assess cytokine production, phagolysosomal acidification, and transcriptomic analysis ... from macrophages, ...

Autophagy involves the formation of autophagosomes, double-membraned vesicles that engulf damaged organelles, misfolded proteins, and pathogens for degradation in the lysosomes (Levine and Kroemer ...

While PSEN1 prefers to bask on the cell surface and sometimes ventures into the early endosomes, PSEN2 contains a sorting sequence that strictly restricts it to late endosomes and lysosomes. As such, ...

Ocean acidification is an urgent environmental challenge caused by rising atmospheric carbon dioxide (CO2) levels, mainly due to human activities. It involves a continuous decrease in the pH of ocean ...