Feb. 10, 2025 — Rapid weight loss affects muscle mass and can increase the risk of osteoporosis. But now there is good news for people taking weight loss medication who may be at risk.

Cathepsin K inhibitors and RANKL antibodies have been ... mass represent exciting opportunities for future drug development. Osteoporosis results in over nine million fractures per year at a ...

Anti-osteoporosis drug targets are currently emerging, but most drugs in clinical trials are still focused on conventional targets. Sclerostin, a 22-kDa glycoprotein secreted primarily by osteoblasts, ...

Due to the widespread presence of PDE7 in various tissues, the development of PDE7 inhibitors has been limited by potential adverse side effects. Japan Tobacco divulges PDE7A inhibitor for ...

Though vitamin K may be less well-known than vitamins C or D, it is no less vital. The vitamin is essential for proper blood clotting, bone health, prevention of osteoporosis, heart health ...

We sought to further explore the relation between duration of exposure to proton pump inhibitors and osteoporosis-related fractures. METHODS: We used administrative claims data to identify ...

Department of Chemical Biology, Helmholtz Centre for Infection Research, Inhoffenstr. 7, Braunschweig 38124, Germany German Center for Infection Research (DZIF), Hannover-Braunschweig Site, ...

Key Laboratory for Ultrafine Materials of Ministry of Education, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Engineering Research Center of Biomedical Materials Ministry of ...

These next-generation STAT6 inhibitors demonstrate excellent oral bioavailability, cell permeability, and metabolic stability, and do not target STAT6 for degradation. DeepCure expects to select a ...