RanBPM (Ran-binding protein in the microtubule-organizing center) is a protein that plays a crucial role in various cellular processes, including signaling pathways, cell cycle regulation ...

This review explores the multifaceted functions of GSPT2, highlighting its involvement in cell cycle regulation and signaling pathways, as well as its potential as a tumor biomarker. By analyzing the ...

According to this model, mutant KRAS is able to hydrolyze guanosine triphosphate (GTP) and cycle ... effector pathway in pancreatic ductal adenocarcinoma (PDAC) models, with its signaling ...

In a nutshell A common desert plant called Artemisia herba-alba contains compounds that can effectively kill colorectal ...

The formation of a complex organism from a single cell is one of the most amazing wonders of biology ... pinpointing possible targets for therapeutic approaches. Keywords: Signaling pathways, Embryo, ...

Skeletal remodeling is mediated by the integrated and tightly coupled actions of mechano-sensing osteocytes, bone-resorbing osteoclasts and bone-forming osteoblasts (Figure 1).

Bone mass and strength are maintained by the bone remodeling cycle involving the integrated ... RANKL/osteoprotegerin/RANK signaling regulates bone resorption and is essential for ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

In multicellular organisms, phosphorylation-based signaling ... (what the cell does in response). What the research team realized—and set out to prove—was that each cycle in a cascade can ...

In multicellular organisms, phosphorylation-based signaling ... (what the cell does in response). What the research team realized -- and set out to prove -- was that each cycle in a cascade ...