Immunologic checkpoint blockade with antibodies against the programmed cell death protein-1 (PD-1) or its ligand (PD-L1) is an effective method for reversing cancer immunosuppression and thereby ...

Researchers reveal that gut microbiota influence the effectiveness of immune checkpoint inhibitors (ICIs) in cancer treatment ...

and programmed cell death ligand 1 (PD-L1) is its ligand protein molecule, both of which are immune checkpoint molecules. An immune checkpoint is an inhibitory pathway of the immune system that is ...

This is achieved by cell extrusion programs, a checkpoint mechanism eliminating ... impact on the fate of extruding cells governing their death or survival. The results recently published in ...

Tislelizumab is BeiGene’s programmed cell death protein 1 (PD-1) checkpoint inhibitor and Anktiva is an interleukin-15 (IL-15 ...