Errors in these checkpoints can have catastrophic consequences, including cell death or the unrestrained growth that is cancer. Another important checkpoint takes place later in the cell cycle ...

and programmed cell death ligand 1 (PD-L1) is its ligand protein molecule, both of which are immune checkpoint molecules. An immune checkpoint is an inhibitory pathway of the immune system that is ...

Researchers reveal that gut microbiota influence the effectiveness of immune checkpoint inhibitors (ICIs) in cancer treatment ...

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed.

Immunologic checkpoint blockade with antibodies against the programmed cell death protein-1 (PD-1) or its ligand (PD-L1) is an effective method for reversing cancer immunosuppression and thereby ...

New research highlights the potential of the novel diagnostic tool iFRET to determine immunotherapy outcomes in stage 2 ...

Tislelizumab is BeiGene’s programmed cell death protein 1 (PD-1) checkpoint inhibitor and Anktiva is an interleukin-15 (IL-15) superagonist from ImmunityBio. The trial aims to confirm the safety and ...