γδ T 细胞独特的抗原识别模式，与传统免疫细胞的识别模式不同。它不像自然杀伤（NK）细胞激活那样，通过激活受体和抑制受体的相互调节来实现快速反应；也不像 αβ TCR 那样，识别抗原肽和 MHC 复合物。γδ TCR 主要利用 CDR3δ 序列的保守侧翼区域结合配体，决定了其识别的蛋白配体种类有限，这种独特的模式可视为模式识别机制的一种补充。

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