Researchers reveal that gut microbiota influence the effectiveness of immune checkpoint inhibitors (ICIs) in cancer treatment ...

Immune checkpoint molecules play a crucial role regulating immune responses, maintaining a balance between fighting diseases and preventing excessive inflammation. These molecules either enhance or ...

Cancer immunotherapies targeting immune checkpoint molecules have revolutionized treatment across various cancer types, significantly improving patient outcomes. Treatments can be limited in some ...

The difficulty in targeting immune checkpoint proteins is their flat and dynamic surfaces, which don't bind small molecules easily. To address this issue, Gabr and Abdel-Rahman looked to the co ...