Codon optimization takes into account factors such as codon usage bias, tRNA abundance, GC content, and RNA secondary structure. By carefully selecting codon combinations, researchers can improve ...

Apart from these studies on regulatory RNAs, recent genome-wide research also reveals the general role of mRNA structure in a variety of post-transcriptional ... A recent study combining genome-wide ...

You can create a release to package software, along with release notes and links to binary files, for other people to use. Learn more about releases in our docs.

As synthetic biology and biotechnology continue to advance, researchers and manufacturers face a critical challenge: how to efficiently produce high-value proteins at scale while maintaining quality ...

Department of Chemistry, University of California, Berkeley, California 94720, United States Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, United ...

This short manuscript uses mutation counts in phylogenies of millions of SARS-CoV-2 genomes to show that mutation rates systematically differ between regions that are paired or unpaired in the ...

Abstract: Understanding protein secondary structure is crucial for analyzing their functions and designing drugs. Accurately predicting its eight states is both vital and challenging. Despite numerous ...

Abstract: Wind power clean energy has become a hot spot in human activities. In response to the problems of security risks and low efficiency in the process of wind turbine hoisting, a new nonlinear ...