Platelets play an important role in atherothrombotic disease. The currently available antiplatelet drugs target key steps of platelet activation including thromboxane A 2 synthesis, ADP-mediated ...

Common antiplatelet medications include aspirin, which inhibits the enzyme cyclooxygenase-1 (COX-1), and clopidogrel, which ...

While a significant number of DES thrombosis occurs while under dual antiplatelet therapy, the identification of low responders to antiplatelet therapy could help reduce these events with more ...