A new class of lipids developed by Penn Engineers improve the rates at which lipid nanoparticles (LNPs) successfully deliver ...

Studies by HighField Biopharmaceuticals Show Advantages of Lipid Structure Design for Applying LNP Non-Viral Gene Therapies to Complex Diseases ...

Center for Translational Biomedical Research, University of North Carolina at Greensboro, Kannapolis, North Carolina 28081, United States Department of Chemistry & Biochemistry, University of North ...

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex (the large protein and phosphoprotein). Not only that, but they also ...

Integral membrane proteins carry out essential functions in the cell, and their activities are often modulated by specific protein-lipid interactions in the membrane. Here, we elucidate the intricate ...

ApoB-100’s massive size and association with lipids in LDL have frustrated conventional approaches to studying its detailed structure ... and visualized LDL in a complex with the ligand-binding ...

Lipids are hydrophobic or amphiphilic small molecules that include sterols, waxes, fatty acids and phospholipids, and are insoluble in water and soluble in organic solvent. Biological lipids are ...

Department of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, SE-75124 Uppsala ,Sweden ...

A novel mechanism that enables cells to maintain energy production even when their main power supply drops/fails has been ...