Understanding bacterial growth mechanisms can potentially help uncover novel drug targets that are crucial for maintaining cellular viability, particularly for bacterial pathogens. In this important ...

Integral membrane proteins carry out essential functions in the cell, and their activities are often modulated by specific protein-lipid interactions in the membrane. Here, we elucidate the intricate ...

The two studies support HighField’s approach for designing LNPs with stable lipid membrane structures (mLNP) and multiple surface anchored antibodies (tLNP) to expand the application of cell and gene ...

Department of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, SE-75124 Uppsala ,Sweden ...

ApoB-100’s massive size and association with lipids in LDL have frustrated conventional approaches to studying its detailed structure ... and visualized LDL in a complex with the ligand-binding ...

In wild-type Lro1, the luminal linker segment retains overall its secondary structure during the simulations and is also relatively stable (Appendix Fig. S7A,B). The predicted helices keep the lipids ...

The work appears in Nature Cell Biology. The research identifies that a nucleolar complex, FIB-1-NOL-56, is a central player in the regulation of proteostasis at the cellular and organismal levels ...

The term "God complex" is used to describe a person who believes they have exceptional power or authority and are superior to others. It is not considered a mental illness on its own, per the ...

Complex post-traumatic stress disorder (C-PTSD) is a mental disorder that develops in response to complex trauma during childhood. Complex trauma is defined as prolonged exposure to traumatic events ...

For the first time, biologists made it happen in the lab. Far from being solo operators, most single-celled microbes are in complex relationships. In the ocean, the soil and your gut, they might ...