Understanding bacterial growth mechanisms can potentially help uncover novel drug targets that are crucial for maintaining cellular viability, particularly for bacterial pathogens. In this important ...

Integral membrane proteins carry out essential functions in the cell, and their activities are often modulated by specific protein-lipid interactions in the membrane. Here, we elucidate the intricate ...

The two studies support HighField’s approach for designing LNPs with stable lipid membrane structures (mLNP) and multiple surface anchored antibodies (tLNP) to expand the application of cell and gene ...

Department of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, SE-75124 Uppsala ,Sweden ...

School of Physics and Astronomy, University of Leeds, Leeds LS2 9JT, U.K. Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, U.K. School of Physics and Astronomy, ...

ApoB-100’s massive size and association with lipids in LDL have frustrated conventional approaches to studying its detailed structure ... and visualized LDL in a complex with the ligand-binding ...

In wild-type Lro1, the luminal linker segment retains overall its secondary structure during the simulations and is also relatively stable (Appendix Fig. S7A,B). The predicted helices keep the lipids ...

The work appears in Nature Cell Biology. The research identifies that a nucleolar complex, FIB-1-NOL-56, is a central player in the regulation of proteostasis at the cellular and organismal levels ...

For the first time, biologists made it happen in the lab. Far from being solo operators, most single-celled microbes are in complex relationships. In the ocean, the soil and your gut, they might ...

Despite its lethality, there is no approved treatment for Nipah virus infection. The viral polymerase complex, composed of the polymerase (L) and phosphoprotein (P), replicates and transcribes the ...