Dextromethorphan HBr 10mg, guaifenesin 100mg; per 5mL; syrup; contains sodium 4mg/5mL; sugar- and alcohol-free.

It acts centrally and elevates the threshold for coughing. It is about equal to codeine in depressing the cough reflex. In therapeutic dosage dextromethorphan does not inhibit ciliary activity.

Background: Dextromethorphan (DM), the d-isomer of the codeine analog levorphanol, is an active ingredient present in a variety of cough and cold remedies. Recently, data generated from a study in ...