(B) HEK293T cells were cotransfected with MmMYL3-Flag and CP-Myc plasmids. MmMYL3 (green) and CP (red) were detected by immunofluorescence staining with anti-Flag or anti-Myc abs, respectively.

This important study reveals a critical role of the transcription factor NR2F2 in mouse fetal Leydig cell (FLC) differentiation. With elegantly carried out experiments, the authors provide compelling ...

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

Cancer researchers at the University of Leicester have developed a technique that could predict how well some breast cancer ...

Jan. 3, 2025 — Biologists have shown that the surfaces of plant leaves are coated with a diverse array of RNA molecules. The finding suggests that the RNA present ...

These regulators are known as MYB, HDAC2, and FOXA2 and when they were suppressed in colon cancer cells, the cells switched back to a normal-like state, removing the cancer threat without ...

Experiments show that IL-23R levels in the bloodstream increase with age and can decrease, reflecting senescent cell clearing, with senolytic therapies. Cellular senescence occurs when cells stop ...

Investigators from Cedars-Sinai and the University of California, San Francisco (UCSF) have identified a new way to deliver instructions that tell stem cells to grow into specific bodily ...

To image the cells expressing microRNA, mCherry fluorescence was used as an indicator of transfected ... and incubated with secondary antibody and 1 µg/ml 4′,6-diamidino-2-phenylindole (DAPI) diluted ...