Cancer researchers at the University of Leicester have developed a technique that could predict how well some breast cancer ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

This important study reveals a critical role of the transcription factor NR2F2 in mouse fetal Leydig cell (FLC) differentiation. With elegantly carried out experiments, the authors provide compelling ...

Their collaboration has resulted in engineered cells called ‘synthetic organizers’ that deliver instructions to stem cells, telling them to grow into specific tissues and organs.

These regulators are known as MYB, HDAC2, and FOXA2 and when they were suppressed in colon cancer cells, the cells switched back to a normal-like state, removing the cancer threat without ...

Experiments show that IL-23R levels in the bloodstream increase with age and can decrease, reflecting senescent cell clearing, with senolytic therapies. Cellular senescence occurs when cells stop ...

Professor Kwang-Hyun Cho remarked, "The fact that cancer cells can be converted back to normal cells is an astonishing phenomenon. This study proves that such reversion can be systematically induced." ...

A large-scale single-cell study shows aging happens in specific stages driven by molecular cues, offering targets to modify the aging process and revealing key age and sex-related cellular differences ...

Investigators from Cedars-Sinai and the University of California, San Francisco (UCSF) have identified a new way to deliver instructions that tell stem cells to grow into specific bodily ...

To image the cells expressing microRNA, mCherry fluorescence was used as an indicator of transfected ... and incubated with secondary antibody and 1 µg/ml 4′,6-diamidino-2-phenylindole (DAPI) diluted ...