Dendritic cells (DC) offer hope that the treatment of end-stage cancer will become much more successful in the near future. Hundreds of dendritic cell-based therapeutic vaccines have already been ...

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This manuscript describes a potentially important theoretical framework to link predictive coding, error-based learning, and neuronal dynamics. The provided evidence is solid, but some details would ...

The modelling is convincing and could be broadly applied to other similar questions. The work will be of interest to neuroscientists studying dendritic development and connectivity at a single-cell ...

At distal dendritic locations, appropriately timed EPSPs or oscillations could increase the amplitude of backpropagating action potentials by three- to fourfold. This amplification was greatest ...

At P15, endosomes are rapidly recruited to enlarge spines. At immature and adult ages, the dendritic shaft contains SER that forms bridges where glutamate receptor trafficking is slowed in regions of ...

Critical experimental evidence for a negative impact on these mechanisms in animal models of Alzheimer’s has been obtained in dual patch recordings in rat hippocampal tissue slices, in which aβ ...