Epidermal involvement appears as brown discoloration, dermal as blue-gray, and mixed epidermal and dermal as brown-gray. Examples of epidermal melanocytotic hyperpigmentation include simple ...

In chronologically aged skin, the epidermis is atrophic, with flattening of the dermal-epidermal junction and loss of rete pegs (Kurban & Bhawan, 1990). The dermis also becomes thinner ...

Experiments in the 1960s had revealed that the fibroblast-containing dermal compartment of the skin determines the identity of the outermost skin layer, the epidermis, in mammals. When researchers had ...

Our data are consistent with a central role of IGF-I stimulation of epidermal keratinocytes; however, a contribution from the potential IGF-I stimulation of dermal immune cells cannot be ruled out ...