Unfortunately, there isn't an enzyme for many reactions we would sorely like to catalyze—things like digesting plastics or ...

As the global population continues to grow, innovative solutions are needed to ensure food security. With limited land and ...

In traditional directed evolution approaches ... or when more than one property is being selected for. “We need the enzyme to be highly active, stable in the process, and tolerant of high ...

Enzymes are proteins – large molecules that do the behind-the-scenes work that keep all living things alive. These proteins are made up of amino acids, a set of building blocks that can be stitched ...

Researchers found that using a process called directed evolution, in which the amino acid sequence of an enzyme is randomly changed until it can perform a desired function, proved much more fruitful.

To overcome these hurdles, a team of researchers, led by Professor Anthony Green and Professor Igor Larrosa, have used directed evolution to develop a new enzyme capable of catalyzing S N Ar ...

By using automated directed evolution, the researchers were able to further engineer this enzyme to have the desired characteristics. The team evaluated more than 4,000 clones before identifying ...