While celebrities like Michael J. Fox and Brett Favre have been open about their struggles with Parkinson's disease, it can ...

Here, in bone marrow transplantation and organoid culture models, T-cell-derived Interferon-γ is shown to promote STAT1-dependent intestinal stem cell c-MYC expression and epithelial regeneration.

A groundbreaking discovery by scientists at Japan’s RIKEN Center for Brain Science has revealed an unexpected link between dopamine and ... damaging brain cells. Over time, this process leads ...

Multiple lines of evidence indicate that altered dopamine signaling may be involved in neuropsychiatric disorders and common behavioral traits. Here we critically review evidence collected during the ...

This study presents a valuable finding on a potential signaling pathway responsible for the direct effects of nicotine on intestinal stem cell growth and tumorigenesis. The evidence supporting the ...

Whereas, all models are restricted to mice, lacking analysis of human samples or human intestinal organoids to prove the human relevance of these findings. Overall, the presented results support their ...

After years of controversy, stem cells are on the cusp of cures for conditions like epilepsy and type 1 diabetes. California Institute for Regenerative Medicine, Neurona Therapeutics, Vertex ...

By uncovering how cells communicate to maintain protein integrity, we're opening the door to the development of preventive therapeutic approaches that could delay disease onset and significantly ...

tu-dresden.de Objective The intestinal epithelium is a rapidly renewing tissue which plays central roles ... to 5 (complete necrosis). Finally, the numbers of necrotic cells were counted in five HPF ...

A research team from Lund University in Sweden is conducting a clinical trial targeting 12 patients with Parkinson's disease using dopamine cells derived from embryonic stem cells in collaboration ...