Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...

The evolution of robust and flexible defense responses has been driven by the diverse and adaptive nature of foreign threats. To maintain its effectiveness, the immune system produces highly ...

To create one of the most advanced immunotherapies in cancer, CAR-T cell therapies, scientists engineer immune T cells to carry a synthetic protein on their surfaces. This protein, called the ...

The PRIMER cells expressed a new transcription factor—a type of protein that regulates gene expression—called GT-3a, which is likely an important upstream alarm for alerting other cells to an ...

The immune cells are postulated to exert a pivotal role in the development of fibrotic skin disease. Single-cell RNA sequencing has been used to explore the composition and functionality of immune ...

New research from Salk Institute scientists reveals how plant cells switch roles to protect themselves against pathogens. When a threat is encountered, the cells enter a specialized immune state ...

The goal of the transplant is to replace the patient’s hematopoietic stem cells – cells that rejuvenate supplies of blood and immune cells – with donor stem cells that are not cancerous. In addition, ...

Their study in mice found that during periods of low energy— such as intermittent fasting—ILC2 immune cells step in to regulate blood sugar levels, acting as a “postman” in a previously ...

The cytokine IL-33 and ILC2 immune cells are critical to TLS formation Previous research published in Nature by Dr. Balachandran's team found that an unusual type of immune cell called group 2 ...

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...