Nevirapine and efavirenz are recommended as key drugs ... NNRTI-resistance mutations & their mechanism of drug resistance The most prevalent NNRTI-resistance mutations are K103N, Y181C and G190A.

Spanish researchers found that high plasma efavirenz levels correlated with CNS symptoms even after weeks or months of treatment. However, in a substudy of an ACTG trial, late neuropsychiatric ...

Defense mechanisms are rooted in Freud’s theory of personality.According to his model, the mind has three dueling forces: the id (unconscious and primitive urges for food, comfort, and sex), the ...

As an additional means of meeting these targets, the Kyoto Protocol introduced three market-based mechanisms, thereby creating what is now known as the carbon market. Stimulate sustainable development ...

The most commonly mutated ALS-linked genes are reviewed with an emphasis on disease-causing mechanisms. The cellular processes involved in ALS pathogenesis are discussed, with evidence implicating ...

Separately, researchers are conducting a study at the Amsterdam University Medical Center involving a different HIV medicine, efavirenz. This line of inquiry follows animal model and stem cell ...

Structural and cellular assays and molecular dynamics simulations reveal the mechanism of action of γ-glutamyl carboxylase, which involves cholesterol and vitamin K. Protein kinase R-like ...

Despite the progress achieved in preventing diseases from the poliovirus and retroviruses, these microbes may cause motor neuron diseases in SSA. The immune mechanisms involved in these neurological ...

Reaction formation is a defense mechanism in which people express the opposite of their true feelings, sometimes to an exaggerated extent. For instance, a man who feels insecure about his ...

Get Instant Summarized Text (Gist) Artificial motors have been developed to mimic muscle proteins, converting chemical energy into mechanical work. These nanoscale rotary motors, embedded in ...

Objective Cardiovascular disease (CVD) is one of the leading non-AIDS-defining causes of death among HIV-positive (HIV+) individuals. However, the evidence surrounding specific components of CVD risk ...