Even old, degraded DNA yields enough signal to perform the analysis. For maximum signal strength I have optimized the protocol, and several points have to be kept in mind: (1) Fluorescent-labeled ...

convert it into complementary DNA (cDNA), and label the cDNA with a fluorescent dye. The fluorescently labeled cDNA is then added to a glass slide or silicon chip upon which thousands of tiny dots ...

Kyushu University Ochiai and his colleagues tested this theory using seq-DNA/RNA-IF-FISH, a sophisticated imaging method that uses fluorescent probes to label DNA, RNA, and proteins. Thanks to ...