Xin et al. investigated the spatial distribution of TLS in non-small cell lung cancer (NSCLC), dividing tumor samples into intratumoral (IT), invasive margin (IM), and peritumoral (PT) regions. They ...

Throughout the follicular phase, a single "dominant follicle" develops faster than the rest. This follicle (a fluid-filled sac in your ovary) then releases more estrogen into the body in ...

It has been attempted to use morphometry, as a part of quantitative pathology, to classify tissue lesions in a metric (and preferably more objective; Figure 4) mode compared with the subjective ...

The tissue adjacent to a tumor behaves differently than areas farther away: The tumor’s cancerous cells influence their surroundings, blocking the body’s immune defenses and creating a sort of haven ...

We discuss the challenges such as immunosuppressive microenvironment, tumor heterogeneity, and physical barriers that limit CAR-T efficacy. Emerging strategies, such as logic-gated and dual-targeting ...

The stage of a cancer describes how far it has spread. To a large extent, your child’s treatment and prognosis (outlook) will depend on the stage, histology, and risk group of their Wilms tumor.

Treatment for Wilms tumor is based mainly on the cancer’s stage and its histology, as described in detail below. In the United States, most children with Wilms tumors are treated in clinical trials ...