Department of Neurosurgery, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, No. 152 Aiguo Road, Nanchang, Jiangxi 330006, China Department of ...

Among the inflammatory mechanisms, TCM for cardiotoxicity involves only two pathways, NF-κB and NLRP3, but other inflammatory pathways such as STAT1 and STAT3 also play important roles in the ...

In this study, we investigated the expression changes and interactions between miR4298 and lncKRTAP5-6-3 in chronically UVB-damaged human keratinocyte cell line (HaCaT) cells and explored miR4298-MAPK ...

SYK-dependent signals from the pre-BCR then feed into the PI3K pathway through CD19 and/or BCAP, leading to the activation of PKB and, in turn, to the inactivation of FOXO transcription factors.

Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced its 2025 priorities and upcoming ...

AF6 denotes afadin, GAP GTPase-activating protein, GEF guanine exchange factor, MEK mitogen-activated protein kinase ... ERK signaling. Together, these studies uncover novel compensatory pathways ...

Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

This important study investigates the signaling pathways regulating retinal regeneration. Convincing evidence shows that the sphingosine-1-phosphate (S1P) signaling pathway is inhibited following ...

In flies defective for axonal transport of mitochondria, the authors report the upregulation of one subunit, the beta subunit, of the heterotrimeric eIF2 complex via mass spectroscopy proteome ...

Here, our current understanding of the MAP kinase pathway is reviewed, as well as recent advances in the design of novel agents that are able to modulate the activity of these signalling cascades.

Could nanotechnology improve exercise performance? Evidence from animal studies Lima, M.R. Moreira, B.J. Bertuzzi, R. Lima-Silva, A.E.