This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

It feels like the Splinter Cell remake has been on its way for a while now, which isn't helped by the fact it's been over three years since we heard anything official about the game. From what we ...

One Of The Most Ambitious Sci-Fi Movies Of The Decade Finds An Audience On Prime Video Wall of ice the size of Rhode Island heading toward penguin-packed island off Antarctica MLB owners ...

29,097 people played the daily Crossword recently. Can you solve it faster than others?29,097 people played the daily Crossword recently. Can you solve it faster than others? I was in the packed ...

29,097 people played the daily Crossword recently. Can you solve it faster than others?29,097 people played the daily Crossword recently. Can you solve it faster than others? Elizabeth Warren ...

While Dallas-Fort Worth has been experiencing near-freezing temperatures of late, the Metroplex’s office market is starting to warm up. Leases were signed on 3.8M SF of DFW office space in the ...

It was a chilly finish to the week across Central and Eastern Kentucky as a reinforcing shot of colder air moved in behind a departing frontal system. After starting the day in the mid-teens ...

If one pipe freezes, others may freeze, too. Call a licensed plumber if you are unable to locate the frozen area, if the frozen area is not accessible, or if you cannot thaw the pipe. If you need ...