Adhesion G protein-coupled receptors (GPCRs) are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for ...

They also realized that the β-adrenergic receptor was one of many in a whole family of receptors that function in the same way. This family is now known as G-protein-coupled receptors, and the studies ...

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their environments-water, lipid membranes, or other condensed phases-are critical to their ...

EPFL researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel ...

The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...