Septerna has a market cap of $750mn and $130mn in cash and ST investments. Discover SEPN's groundbreaking drug discovery ...

Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology ...

Announcing a new article publication for BIO Integration journal. Diabetes, a common metabolic condition, poses a substantial health burden worldwide. To revolutionize diabetes management, enhance ...

EPFL researchers have developed a computational method to explicitly consider the impact of water while designing membrane ...

Scientists at the Faculty of Medicine have now developed an innovative numbering system for the GAIN domain, a protein domain ...

This review examines the cardiovascular risks associated with cannabis, revealing its potential to cause severe heart health ...

Researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel drug ...

Figure 3. Heatmap of the dysregulated genes involved mitochondria dysfunction in space. One of the dysregulated pathways that is not in Figure 2 is G-protein coupled receptor (GPCR) signaling, which ...

In muscle tissue, Activin interacts with the Activin RII receptor, triggering intracellular signaling pathways. Activin RII phosphorylates Activin RI, which activates the Smad2/3 signaling pathway.