1.2.3 The mouse as a model prior to the recombinant DNA revolution With the demonstration in the mouse of genetic factors that impact upon cancer, millions upon millions of animals were used to ...

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50% in a mouse model of the fatal neurodegenerative ...

In attempting to engineer a genetic mouse model for a human disorder, for example, it is important to know what kind of mutation causes the disease (for example, is the disease null, hypomorphic ...

Using cutting-edge stem cell technology, a team of scientists from the Chinese Academy of Sciences (CAS) recently created a ...

In two new papers, researchers from The Jackson Laboratory (JAX) report the successful use of two approaches -- gene therapy ...

Genetic changes are a significant cause of infertility, impacting over 15% of the global population. TLE6, a major protein ...

Collaborative research is driving the development of future treatments to ease symptoms of autism and epilepsy. The ...

Intestinal fibrosis, as a late-stage complication of inflammatory bowel disease (IBD), leads to bowel obstruction and requires surgical intervention, significantly lowering the quality of life of ...