Macrophage exposure to oxidized LDLs (oxLDLs) or to necrotic plaque debris enriched with oxysterols induces HIF-1α -dependent pathways. Moreover, HIF-1α is involved in many oxLDL-induced effects in ...

Here, we screened proteins interacting with SHP2 in decidual hTERT-immortalized human endometrial stromal cells (T-HESCs) and identified Hypoxia-inducible factor-1 (HIF-1) signaling pathway as a ...

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Title ” The PAQR-2 and HIF-1 pathways are physiologically essential for unsaturated fatty acid homeostasis in C. elegans ” Opponent Professor Jennifer Watts, School of Molecular Biosciences, ...

As a consequence, the terminal pathway of preeclampsia, an exaggerated maternal systemic inflammatory and anti-angiogenic condition, occurs. The frequency and severity of placental developmental ...

Day of Atonement; the scapegoat; the eating of blood forbidden; civil and religious laws; immorality forbidden We should also forgive and choose not to remember offenses against ourselves or others.

To answer this question, the authors used a combination of in vivo and ex vivo experiments in mice to demonstrate ligand-independent activation of Notch1 by circulation induced-mechanical stress and ...

FGFR3 deficiency in myeloid cells also aggravated joint destruction in DMM mouse model. Mechanically, FGFR3 deficiency promoted macrophage chemotaxis partly through activation of NF-κB/CXCR7 pathway.