Why is knowing the atomic structure of molecules useful? Learn why, and how information like this about protein structure is shared through a publicly available database.
However, the role of hemoglobin in the understanding of genetic disease has been equally powerful. Over 300 abnormal hemoglobins — such as sickle cell hemoglobin — have been discovered ...
SAN DIEGO -- Treatment with hydroxyurea led to more hematologic dose-limiting toxicities (DLTs) compared with placebo in patients with hemoglobin SC, a milder form of sickle cell disease (SCD), a ...
Sickle cell hemoglobin (HbS) behaves like normal hemoglobin when fully oxygenated, but at low oxygen tension the hydrophobic valine residues cause the HbS to polymerize, resulting in gel formation ...
Professor Yuet Wai Kan and his team from University of California, San Francisco using gene therapy has replaced the genes responsible for causing sickle cell anemia in bioengineered mice with ...