Why is knowing the atomic structure of molecules useful? Learn why, and how information like this about protein structure is shared through a publicly available database.
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Hydroxyurea Shows Some Benefits in Milder Sickle Cell DiseaseSAN DIEGO -- Treatment with hydroxyurea led to more hematologic dose-limiting toxicities (DLTs) compared with placebo in patients with hemoglobin SC, a milder form of sickle cell disease (SCD), a ...
Sickle cell hemoglobin (HbS) behaves like normal hemoglobin when fully oxygenated, but at low oxygen tension the hydrophobic valine residues cause the HbS to polymerize, resulting in gel formation ...
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A sickle cell first: Base editing, a new form of gene therapy, leaves patient feeling 'more than fine'"Sickle cell disease has a broad spectrum of severity ... instructions for his red blood cells to make a fetal form of hemoglobin. (Unlike "adult" hemoglobin, fetal hemoglobin doesn't cause ...
How do mutations happen, and how do they influence the future of a species? Molecules of sickle-cell hemoglobin stick to one another, forming rigid rods. These rods cause a person's red blood ...
Professor Yuet Wai Kan and his team from University of California, San Francisco using gene therapy has replaced the genes responsible for causing sickle cell anemia in bioengineered mice with ...
IMMvention Therapeutix, Inc., a Durham early-stage biotechnology company focused on discovering and developing human ...
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