Figure 1: Heparan sulfate proteoglycan is a receptor for AAV-2 virions. Identification of the AAV receptor and vector-specific reagents has led to the development of purification protocols for ...

Although AAV uses the ubiquitously expressed cell surface heparan sulfate proteoglycan (HSPG) as a receptor, the transduction efficiency of AAV vectors varies greatly in different cells and ...

Proteoglycans are present in different forms within different types of extracellular matrices and connective tissues. Heparan sulfate proteoglycans (HSPGs) are known to play important structural and ...

Sulfated glycosaminoglycans (GAGs), along with the proteoglycan aggrecan, are known to increase with tendon pathology ... histochemical technique and immuno-histological technique with antibodies ...

Based on neurite outgrowth assays, we have previously isolated, cloned, and produced as recombinant proteins two ligands of heparan sulfate proteoglycans ... to the transmembrane proteoglycan syndecan ...