Figure 1: Heparan sulfate proteoglycan is a receptor for AAV-2 virions. Identification of the AAV receptor and vector-specific reagents has led to the development of purification protocols for ...
Although AAV uses the ubiquitously expressed cell surface heparan sulfate proteoglycan (HSPG) as a receptor, the transduction efficiency of AAV vectors varies greatly in different cells and ...
Sulfated glycosaminoglycans (GAGs), along with the proteoglycan aggrecan ... and immuno-histological technique with antibodies against Dermatan Sulfate, Chondroitin Sulfate, Heparan Sulfate and ...
Based on neurite outgrowth assays, we have previously isolated, cloned, and produced as recombinant proteins two ligands of heparan sulfate proteoglycans (HSPGs ... through binding to the ...