As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Histologic assessment of a liver biopsy specimen remains the gold standard for quantifying fibrosis, with increasing interest in the use of noninvasive markers to allow more frequent sampling and ...

jpi{at}soton.ac.uk BACKGROUND Activated hepatic stellate cells (HSC) are central to the pathogenesis of liver fibrosis, both as a source of fibrillar collagens that characterise fibrosis and matrix ...

Background: Hepatic stellate cells (HSCs) are a major fibrogenic cell type that contributes to collagen accumulation during chronic liver disease. With increasing interest in developing antifibrotic ...

The liver is composed of parenchymal cells (hepatocytes) and non-parenchymal cells, with liver non-parenchymal cells mainly encompassing LSEC, hepatic stellate cells, Kupffer cells, and immune cells.

Hepatic macrophages are a remarkably heterogeneous population consisting of self-renewing tissue-resident phagocytes, termed Kupffer cells (KCs), and recruited macrophages derived from peritoneal ...

In 2023, the global hepatic markers market is expected to be worth USD 2.3 billion. The market is expected to reach USD 4.2 billion by 2033, expanding at a 6.2% CAGR throughout the forecast period.

近日，中国科学院广州生物医药与健康研究院和海军军医大学附属东方肝胆外科医院合作在Hepatology发表了题为Lhx2 specifically expressed in hepatic stellate cells promotes liver regeneration and inhibits liver fibrosis的研究论文 近日，中国科学院广州生物医药与健康研究院和海军军医 ...

Our mission is to provide a state-of-the-art facility, expertise, and education in advanced quantitative light microscopy to support Drexel University’s research community The Cell Imaging Center (CIC ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.