This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...

The structure of the EphA4 receptor SAM domain ... 1 μl of 100 mg ml –1 native or mutant (E941C) protein in 7 mM Hepes pH 7.5 were mixed with equal volumes of reservoir buffer containing ...

Here, we describe structures of the Nipah virus L-P polymerase complex and the L-protein’s Connecting Domain (CD). The cryo-electron microscopy L-P complex structure reveals the organization of the ...

Capital structure is the mix of debt and equity that fund a company's operations. A judicious use of debt and equity is a key indicator of a strong balance sheet. A healthy capital structure that ...

i. Grow 1–3 L of K562 cells in spinner flasks with gentle agitation in basal RPMI medium supplemented with 25 mM HEPES-NaOH pH 7.4. ii. Monitor cell growth and viability daily, carefully maintaining ...

In addition to reaction optimization, this work also involves product characterizations regarding chemical structure, morphology, anti-inflammatory activity, and cytotoxicity. With our goal of making ...