The recently discovered Hippo pathway might have a critical role in controlling organ size and homeostasis in many organisms from Drosophila to mammals. You have full access to this article via ...

Recent studies using genetically engineered mouse strains have shed new light on this problem; the Hippo signalling pathway, first elucidated as a regulator of organ size in Drosophila ...

For example, the Hippo pathway was discovered in Drosophila around 20 years ago, and only recently did the first Hippo targeted therapies enter clinical trials for human cancers. Excitingly ...