Structural variants in the human genome include cytogenetically detectable and submicroscopic deletions, duplications, large-scale copy-number variants, inversions and translocations. The ability ...
Scientists at deCODE genetics/Amgen have constructed a complete map of how human DNA is mixed as it is passed down during reproduction. The map marks a major step in the understanding of genetic ...
It’s a marvel how the human genome — two meters of DNA — fits into the tiny nucleus of a cell while orchestrating the complex processes that sustain life. A new study from Northwestern Engineering’s ...
Read the paper: Heritable polygenic editing as a potential frontier in genomic medicine The study reveals that polygenic genome editing in human embryos could substantially reduce the likelihood ...
The most advanced engineering of human cell lines to date has been accomplished by scientists, demonstrating that genomes are more robust against significant structural changes than previously ...