Interferon gamma-1b is under clinical development by Amgen and currently in Phase II for Relapsed Acute Myeloid Leukemia.

Interferon gamma (IFN-γ) is a cytokine that induces a series of immune responses against viruses and tumors. The pro-apoptotic, anti-tumor and anti-proliferative actions of the cells are ...

IFI16 facilitates the inflammatory endothelial pathophenotypes observed among individuals with PAH, according to new research ...

In further analyses in mice and human blood cells ... A likely culprit causing Sjögren's disease symptoms in mice: interferon gamma. "It came down to a defect in regulatory T cells and an ...

how HIF1α in T cells is key for induction of interferon gamma, or IFN-γ, in that hypoxic environment. The cytokine IFN-γ is known to be essential to induce the tumor-killing capacity of T cells.