Interestingly, a substantial number of SLE patients produce IgE autoantibodies, suggesting that basophils may contribute to disease severity through their involvement in Th2-associated immunity[2].

to trigger basophil activation. The fact that in this context the BAT does not discriminate between IgE- and non-IgE-mediated reactions, should not be considered as a shortcoming. Finally ...

A recent study reveals the pivotal role of tristetraprolin (TTP), an RNA-binding protein, in regulating inflammatory responses in basophils, immune cells central to allergic reactions. The research ...

In vitro, omalizumab and human IgE form several immune complexes that vary in size as the 2 components' molar ratios are changed. [29] The largest complex, a stable cyclical hexameric structure ...

Basophils from each strain were stimulated with antigen combined with IgE, IL-33, or lipopolysaccharide (LPS). We measured gene expression, mRNA stability, and inflammatory protein levels.

Basophils from each strain were stimulated with antigen combined with IgE, IL-33, or lipopolysaccharide (LPS). We measured gene expression, mRNA stability, and inflammatory protein levels.

Basophils from each strain were stimulated with antigen combined with IgE, IL-33, or lipopolysaccharide (LPS). We measured gene expression, mRNA stability, and inflammatory protein levels.