Allergy and immunology lost a pioneer last summer with the death of Marcus Maurer, MD, executive director of the Institute of Allergology at Charité University Medicine, Berlin. Maurer was an author ...

A recent study reveals the pivotal role of tristetraprolin (TTP), an RNA-binding protein, in regulating inflammatory responses in basophils, immune cells central to allergic reactions. The research ...

The authors previously discovered that IgE is not readily removed from pDCs using omalizumab to the same extent observed for basophils, suggesting that a portion of the IgE on pDCs may be membrane ...

Basophils from each strain were stimulated with antigen combined with IgE, IL-33, or lipopolysaccharide (LPS). We measured gene expression, mRNA stability, and inflammatory protein levels.

Basophils from each strain were stimulated with antigen combined with IgE, IL-33, or lipopolysaccharide (LPS). We measured gene expression, mRNA stability, and inflammatory protein levels.

with anti-IgE or anti-IgE-receptor I, and fail to upregulate expression of CD63 and/or CD203c. Importantly, as activation of the basophil with N-formyl-methionine-leucine-phenylalanine (fMLP ...

The basophil activation test (BAT) is an in vitro assay ... When ImmunoCAP was available, we compared specific IgE and BAT results by using Cohens' kappa (κ) and revealed a moderate level of agreement ...

极大地丰富并深化了对IgE介导的过敏反应的诊断手段。 1. 流式细胞术的崛起：基础与应用 流式细胞术，凭借其高效、精准和自动化处理的特点，正在逐渐成为过敏性疾病检测的新宠。尤其是针对嗜碱性粒细胞活化试验（Basophil Activation Test，简称BAT）和被动肥大 ...

Medically reviewed by Corinne Savides Happel, MDDifferent types of antibodies are produced by your immune system. These five ...

Previous investigations have shown an association between a T helper cell (Th)2-mediated inflammatory response, for example immunoglobulin E (IgE)-mediated allergy, and a decreased risk of complicated ...

Increasing sensitivity when only the reactions that occurred during the last 3 years before performance of the basophil activation test are taken into account. H: History; NMBA: Neuromuscular ...