Endoscopy (including a jejunal biopsy) revealed a macroscopically and histologically normal upper gastrointestinal tract; however, ileocolonoscopy revealed the presence of multiple aphthous ulcers ...

If this is possible, what is the timing of ileocolonoscopy; 6 months, 3 months, 1 month? Once there is mucosally evident disease, is there an irreversibility and tissue destruction that makes ...