Trapped immune cells laden with microplastics starve the brain of oxygen—mouse study links vascular blockages to memory loss and motor deficits, with lingering risks even after symptoms fade.
Microglia, the brain’s immune cells, play vital roles in clearing toxins and maintaining neuronal health but can also contribute to neurodegenerative diseases if overactive.
In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.
Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor ...
Introducing the M@P nanoplatform: a novel approach to cancer therapy that triggers pyroptosis and ferroptosis, boosting immune responses and treatment efficacy.