Insulin receptor substrate (IRS)-1 is a multitask protein that interacts with many other proteins. IRS-1 is mitogenic, inhibits differentiation, protects from apoptosis and regulates cell (and ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Impaired insulin receptor signaling is ...

There are four major areas of research: 1) Understanding insulin action and insulin resistance. In this area we have projects focusing on the insulin receptor itself, the insulin receptor substrate ...