In conclusion, our study showed that obesity induced by a high-fat diet triggers two significant responses: first, it inhibits the AMPK-dependent Ser372 phosphorylation of SREBP-1c, consequently ...

Insulin-like growth factor-2 (IGF2), which is widely expressed in ... and induces IGF2 production in the hippocampus to improve memory ability. p, phosphorylation; Shc, adaptor protein p66; Grb2, ...

When you have diabetes, insulin is vital to help keep your blood sugar levels in check. If you have type 1 diabetes, you must inject insulin daily. Those with type 2 diabetes may also require ...

The SCAN enzyme employs this mechanism, selectively nitrosylating target proteins such as the insulin receptor and its ... transduction processes like phosphorylation. This discovery challenges ...

Polycystic ovary syndrome (PCOS) can put you at risk for insulin resistance. Watch for symptoms of insulin resistance that are common for females with PCOS. These include cravings and frequent ...

Columbus joined a slough of cities, states and counties in suing drug companies and pharmacy benefit managers who they say artificially raised insulin prices for decades and profited from it ...

After ligand binding, the receptor associated JAKs become active through phosphorylation, and in their turn phosphorylate tyrosine residues in the cytoplasmic portions of the clustered receptors.

He, H.J., Cen, X.H., Liang, Y.J., Zhong, J.M., Deng, J.H. and Jiang, Y.J. (2025) Progress in the Regulation of Lipid Metabolism by the Orphan Nuclear Receptor Nur77. Journal of Biosciences and ...

A single-center pilot study at the Veterans Affairs Hospital/University of Washington in Seattle reported improved verbal memory retention and attention after a three-week test of 20 international ...