Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Impaired insulin receptor signaling is ...

The Discovery of New Members of the TNF Receptor and Ligand Families and Their Relationship to Osteoclasts and Bone Metabolism Binding of RANKL to RANK initiates a signaling cascade, which ...

Ozempic and Wegovy do the same thing as GLP-1 would normally do for you — but to enable them to treat diabetes and obesity, ...

Insulin, IGF1, and IGF2 and their relatively high-affinity receptors, insulin receptor, IGF1 receptor, and IGF2 receptor, are shown. The relative affinity of each ligand for the receptors is ...

Researchers now offer a simplified method they call ProteinReDiff that uses artificial intelligence to speed the redesign of ligand-binding proteins. In biology, the binding of cellular proteins ...

which sustains cell survival and insulin sensitivity. Neuregulin, a Members of the Epidermal Growth Factor Family NRG is released by cells of endothelial, mesenchymal, and neuronal origin, while ErbB ...

The ability to alter protein binding can create tailored therapeutics with reduced side effects, sensitive diagnostic tools, targeted drug delivery and sustainable ...

Ligand Pharmaceuticals Incorporated ... a dual endothelin and angiotensin II receptor antagonist in development for rare kidney diseases and non-immunosuppressive treatment indicated for ...

Our work has generated investment ideas in health care, consumer electronics, finance technologies, transportation, AI-based Oppenheimer raised the firm’s price target on Ligand (LGND ...

Patients with metabolic dysfunction-associated steotohepatitis (MASH) who are already taking a glucagon-like peptide-1 ...