It is produced by macrophages when they are stimulated by interferon-gamma, a signaling protein involved in immune responses. Recent research has highlighted the role of neopterin and other ...
including no dose-limiting toxicities reported to date and consistent interferon gamma signaling observed throughout treatment cycles." "These abstracts support the potential for our TAMP therapy ...
“In addition, the preliminary Phase 1 data we reported today for XTX301, our tumor-activated IL-12, highlight its promising clinical profile, including no dose-limiting toxicities reported to date and ...
As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...
8, 2025 — A study has found targeting a protein called endocan and its related signaling pathway could be a promising new approach for treating glioblastoma, an aggressive and lethal type of brain ...