Pancreatic ductal adenocarcinoma (PDAC) is notorious for a dense fibrotic stroma that is interlaced with a collagen-based extracellular matrix (ECM ... Recent studies have shown that the ECM augments ...

1. Reduction in ECF Volume – A lower intake of water leads to a drop in extracellular fluid, making the skin appear tighter ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

Lung metastases are a devastating reality for over half of cancer patients whose tumors spread beyond their initial sites.

Here, a biosafe porous-MNAE using interstitial fluid (ISF) as conductive fillers is proposed. Its porous-MNs can penetrate the high-impedance stratum corneum (SC) and automatically absorb ISF through ...

Interstitial cystitis (IC) and overactive bladder (OAB) are two distinct but related conditions that affect the bladder and can significantly affect quality of life. IC is also referred to as ...

Specifically, we show that tumor cells subjected to oxidative stress by carbonyl cyanide-3-chlorophenylhdrazone (CCCP) eliminate damaged mitochondria segments by bypassing the lysosome to export them ...

Peter Forrest — who, as P. Fluid, was lead singer and frontman of the pioneering Black rock band 24/7 Spyz — has died at the age of 64. On Jan. 14th, Forrest’s body was found badly beaten in ...

Effects of the TGF-β family on differentiation Several classes of extracellular proteins act as key mediators of differentiation that regulate or define the selection and the progression of the ...

If you have ever run out of windshield washer fluid when you didn’t have any more on hand, you may have wondered whether you really need special fluid or if you could just use plain water instead.