Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of diabetes ... As a result of hyperglycemia, retinal endothelial cells are damaged by ischemia, oxidative ...

Occlusion of retinal microvessels can lead to retinal ischemia and neovascularization ... Retinal tissue comprises multiple cells, so diabetic retinopathy involves pathological changes in different ...

Acute limb ischemia occurs due to a sudden decrease in the blood flow to a limb, resulting in a potential threat to the viability of the extremity. Unfortunately, the threat is not only to the ...

Acute limb ischemia (ALI) results from a sudden obstruction in the arterial flow to the extremity due to an embolism or thrombosis. Embolic problems result in a greater degree of ischemia than ...

Over time type 2 diabetes can affect all body parts, including the feet. When blood sugars are not controlled, moist areas in the feet are prone to infections. People with diabetes can experience ...

Additionally, alpha-lipoic acid could help reduce the pain of diabetic neuropathy. Research on the benefits of many of these supplements is conflicting, however. Supplements may not be right for some ...

15 Other potential drivers of discordance between angina and ischaemia include variations in pain thresholds and cardiac innervation (eg, diabetic neuropathy). The long-term (sometimes lifelong) ...